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5 Benefits of macrobiotic diet and side effects

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Discover the 5 shocking health benefits of a macrobiotic diet and side effects.

The meaning of the macrobiotic diet is “great life.” As stated by the Kushi Institute – one of the world’s leading authorities on the macrobiotic diet

«This is not simply a diet, macrobiotics recognizes the profound effects that food, the environment, activities and attitudes have on our body- mind-emotions ».

The core concepts of the macrobiotic diet, including the Traditional Chinese Medicine belief that it balances yin and yang in both the body and the environment, date back many centuries in ancient Eastern traditions.

Proponents of macrobiotic eating approaches have long encouraged people to eat natural, whole foods that not only support the health of their bodies, but also the ecosystem and natural order of life.

As a “countercultural” approach to eating, macrobiotic diets became fashionable in the United States during the 1960s because they encouraged living in harmony, practicing a positive mindset, and viewing food as much more than just calories or fuel. .

Although each person reacts differently to different dietary approaches, evidence shows that macrobiotic-style diets can help improve heart health, reduce inflammation, and support a healthy body weight well into old age.

What is the macrobiotic diet

The macrobiotic diet is a plant-based diet rooted in yin-yang theory that comes from Asia.

According to macrobiotic theory, the balance between yin and yang is achieved through a mainly vegetarian diet, low in fat, with a balance of different macronutrients (proteins, carbohydrates and fats), foods that have different energy qualities and a wide range of vitamins and minerals from plants.

This approach to eating is believed to better support agriculture, local farming, digestion, and even mental well-being.

Other recommendations for eating a macrobiotic include buying locally grown produce, buying organic foods that are not treated with chemical pesticides, consuming foods in season, consuming mostly fresh and raw foods, and an emphasis on organic foods. plant foods over meat, dairy and other animal products.

Most macrobiotic diets emphasize the consumption of a wide variety of plant foods, which means that these diets tend to be relatively high in carbohydrates.

However, because refined sugar and processed/ packaged foods are not part of the macrobiotic plan, these carbohydrates are “complex,” great sources of dietary fiber, and packed with antioxidants and other nutrients.

Although there are many different varieties of macrobiotic diets that are consumed around the world, most have roughly the following breakdown:

• More than 50 percent of calories come from complex carbohydrates (sometimes even up to 80 percent), 15 to 30 percent from healthy fats, and 10 to 20 percent from protein.

Although carbohydrates are consumed in large quantities, refined carbohydrates such as processed grains and sugar are avoided.

• A high proportion of the carbohydrates in macrobiotic diets (about 25 to 30 percent of total calories) comes from fresh or cooked vegetables.

This is a very high percentage considering how low in calories vegetables naturally are.

• Complex carbohydrates, such as brown rice, barley, millet, oats, and organic (non-GMO) corn are also commonly consumed, accounting for 30 to 40 percent of total calories.

• Many also get 5 to 10 percent of their calories from legumes or beans, often the fermented types like tempeh, miso, or tofu.

• Sea vegetables are a staple in most macrobiotic diets, accounting for 5 to 10 percent of total calories.

• A small percentage, about 5 percent of calories, tend to come from fish or shellfish (usually eaten several

times a week on average).You may notice that macrobiotic diets have a lot in common with the famous Okinawan Diet, which is not surprising considering that both have similar roots in Asian cultures.

The Okinawan Diet is named after the largest island of the Ryukyu Islands in Japan and is consumed by some of the healthiest and longest-lived people in the world.

In fact, Okinawa has been coined as one of the Blue Zones of the world, where people have the highest chance of living in the last 100 years.

The average life expectancy in the United States is 78.8 years, but it is between 80-87 years in Japan (higher for women than for

5 benefits of a macrobiotic diet

Below are the 5 benefits of a macrobiotic diet for health:

1.- Benefits of macrobiotic diet for inflammation

• In 2015, the University of Memphis School of Public Health published the findings of a study investigating the anti-inflammatory and anti-cancer potential of macrobiotic diets.

The study compared the nutrient composition of a macrobiotic diet plan with the National Dietary Recommendations (CDR) based on the National Health and Nutrition Examination Survey (NHANES).

• A key comparison was evaluating which approach scored high on the Dietary Inflammatory Index (DII), as well as comparing levels of total calories, macronutrients, and 28 micronutrients.

• The results showed that the macrobiotic diet plan had a lower percentage of energy from fat, a higher intake of dietary fiber, and higher amounts of most micronutrients.

Nutrients in the macrobiotic diet often met or exceeded the RDA recommendations, with the exception of vitamin D, vitamin B12, and calcium.

• Based on DII scores, the macrobiotic diet was found to be “more anti-inflammatory compared to NHANES data,” and the researchers concluded that the overall findings indicated potential for disease prevention when a macrobiotic eating approach was followed.

2.- Benefits of macrobiotic diet for heart

• Certain studies have found evidence of macrobiotic-style diets that support cardiovascular health, particularly lowering serum lipid levels and lowering blood pressure levels.

This is not surprising considering how many high antioxidant anti-inflammatory foods are encouraged in a macrobiotic diet.

For example, the macrobiotic diet is rich in dietary fiber, including all kinds of fiber-rich foods, such as raw vegetables, beans, and ancient grains.

• Eating plenty of fiber has been correlated with improvements in cardiovascular disease risk factors through multiple mechanisms, including lowering lipids, regulating body weight, improving glucose metabolism, controlling blood pressure, and blood pressure. reduction of chronic inflammation.

3.- It can help maintain a healthy weight

• Like those who eat the Okinawan way, proponents of the macrobiotic diet focus not only on eating the right foods, but also eating them in the correct amounts.

• The macrobiotic diet emphasizes eating carefully, slowing down and savoring meals, paying attention to physical sensations (also called biofeedback), and chewing food thoroughly.

• This approach can help you better control how much you eat, give you more pleasure from having less, teach you to avoid emotional eating out of boredom or other negative feelings, and achieve satiety more easily.

• Rather than trying to lose weight simply by cutting out too much food or consuming less, which can lead you to feel overly hungry and deprived, eating mindfully and choosing foods wisely can help you feel more in touch with your body’s needs.

4.- Very Low in Sugar, Gluten and Packaged Foods

• Like other whole-food-based diets that eliminate junk foods, packaged goods, bottled drinks, fried foods, and fast foods, the macrobiotic diet is very low in sugar, empty calories, and artificial ingredients.

• This makes for a very nutrient-dense diet, high in things like vitamin C, vitamin E, and fiber, but generally low in calories.

• It can also be potentially beneficial for food allergy sufferers as it removes common allergens that can cause indigestion, such as dairy products, almost all gluten, and acorns.

• However, a drawback and point of criticism is that macrobiotic diets tend to include a lot of salty and high-sodium foods, mainly from things like soy sauce, fermented soy products, and sea vegetables.

5.- Benefits of macrobiotic diet for cancer

• Although diet is only one piece of the total puzzle when it comes to preventing cancer, and results vary from person to person, research suggests that consuming a macrobiotic diet may help reduce cancer risk in part by providing high levels of antioxidants and phytoestrogens.

• A 2011 report published in the Journal of Nutrition stated, “Based on the available evidence and its similarity to dietary recommendations for chronic disease prevention, the macrobiotic diet probably carries a reduced risk of cancer.”

• Women who consume macrobiotic diets tend to have modestly lower circulating estrogen levels, which has been linked to a lower risk of breast cancer.

• Macrobiotic diets provide high amounts of phytoestrogens from foods like fermented soy products and sesame seeds , and these can help regulate natural estrogen production by binding to estrogen receptor sites.

• While too much estrogen comes with its own risks, for women over 50 who naturally experience decreased levels during menopause, the extra estrogen from their diets could help lower their risk of cancer, among other benefits.

How to Consume Macrobiotic Diet

Foods that are considered macrobiotics include:

• All types of fresh vegetables other than night shade, especially daikon radishes, cooked or fresh leafy greens such as bok choy, cabbage, mushrooms, chives, leeks, broccoli, carrotsbeets, various varieties of squash, watercress, and cauliflower.

• Fresh herbs, including gingergarlic, coriander, etc., plus soy sauce, tamari, fish sauce, brown rice syrup, and honey for sweetening or flavoring.

• Algae and seaweed

• Beans and legumes, tofu, tempeh, adzuki beans, black beans, and edamame

• Nuts and seeds, including sesame, pumpkinalmonds, and cashews

• Raw old grains – this includes all types of rice (especially brown rice), millet, barley, buckwheat, amaranth, quinoa, rye, oats, and organically grown corn.

• Noodles made from brown rice, soba, and other grains

• Miso or fermented soy seasonings (and miso soup)

• Unrefined oils made from things like sesame or pumpkin seeds

• Tea, such as green, black, jasmine, white, long oo, bancha, dandelion, grass, etc.

Foods to avoid on a macrobiotic diet:

• Packaged and processed foods

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• Dairy products

• Meat

• Eggs

• Refined sugar and sweeteners

• Chocolate or cocoa products

• Most fruits, especially tropical ones

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• Coffee

• Strong or hot spices

Night-shade vegetables: This includes avoiding dark-colored vegetables, such as eggplants, tomatoes, potatoes, and bell peppers. How is that, you may be wondering?

Although belladillas are not a problem for a high percentage of people, some experience digestive symptoms when consuming these foods, including allergies, symptoms of intestinal leakage and autoimmune reactions.

However, eliminating these vegetables in general is a common criticism of the macrobiotic diet as many feel this is not necessary for most healthy people.

Macrobiotic diet plan and lifestyle tips

• Cook fresh food at home more often, especially on a gas stove, which reduces the amount of leftovers and microwave, frozen, or canned food you eat.

• Make plants the center of your meals by only consuming fresh and wild seafood (and especially meat or dairy) in limited quantities.

• Try to eat a variety of colored fruits and vegetables every day, as different colors indicate different antioxidants.

• Drink plenty of clean water and tea, avoiding sweetened beverages, alcohol, and caffeine.

• Try to chew your food well to improve digestion and also slow down during meals. The ideal is to chew up to 25-50 times according to the macrobiotic diet theory.

• Use glass to store food and water instead of plastic products.

• The Great Life Global organization also recommends other macrobiotic lifestyle tips to improve balance, such as opening windows every day for fresh air, keeping plants indoors, walking outside, sticking to a regular sleep schedule.

And wakefulness, practicing gratitude daily, learning to cook at home more often, wearing clothing made from natural fibers, exfoliating with hot towels, or brushing your skin to detoxify and chew your food thoroughly while eating.

Recipes for a macrobiotic diet

For breakfast: a green smoothie, brown rice porridge with nuts and seeds, or a tasty and traditional breakfast of miso soup, vegetables and legumes.

For lunch: miso soup with seaweed, a small amount of wild fish, sautéed vegetables, and a serving of unprocessed grains, such as brown rice. The tea can also be consumed throughout the day.

For dinner: Similar to lunch, such as soup with soba noodles and vegetables, fermented beans or tempeh for protein with seaweed salad, or a stir fry made with vegetables, grains, nuts and seeds.

Macrobiotic diet vs. Paleo diet

• The Paleo diet is modeled after what our ancestors are believed to have eaten thousands of years ago – that is, only natural foods that could have been found within their local environments.

• Because both the macrobiotic diet and the paleo diet emphasize the consumption of organic, unprocessed, local and seasonal foods, the two diets have some underlying principles in common – however, certain foods also differ between the two approaches.

• One of the biggest differences between macrobiotic diets and paleo diets is that macrobiotic diets are plant-based, sometimes even completely vegetarian / vegan.

People who eat a macrobiotic diet get their protein from plant-based foods like tofu, legumes, beans, whole grains, nuts, seeds, and occasionally some shellfish.

• The paleo diet tends to include more animal protein, including meat, fish, eggs, and poultry.

However, both approaches avoid dairy products and all processed vegetarian proteins (such as soy isolate or synthetic protein powders).

• The paleo diet also eliminates all beans, legumes, and grains for the most part, while the macrobiotic diet encourages these foods.

However, both diets reduce or eliminate added sugar, synthetic additives, artificial ingredients, refined oils, fried foods, and sometimes common allergens like belladonna greens and gluten.

Side effects of macrobiotic diet

Although the macrobiotic diet is considered one of the most popular alternative or complementary dietary approaches for the treatment of chronic diseases, including cancer, few studies have been able to really demonstrate its effectiveness in preventing or treating disease.

Therefore, more research is still needed before drawing conclusions about the healing benefits of this diet.

According to some experts, there are concerns regarding treating cancer with dietary approaches, such as macrobiotics, including:

• Patients who potentially delay conventional treatments and doctor visits

• Possibly developing nutritional deficiencies that impair immune function, such as consuming too little vitamin D, calcium, and protein

• Eating too few calories overall, which can cause muscle loss and fatigue – this can be made worse by low levels of iron and vitamin B.

• Some also find that macrobiotic diets have social limitations (due to strict adherence to this diet) that make them difficult to follow.

Additionally, macrobiotic ingredients can be difficult to obtain, and the salt intake in this diet plan is considered too high by some.

There is also disagreement on the need to eliminate most fruits, including all tropical fruits.

These are all valid arguments and should be weighed against your personal preferences, beliefs, and your overall health.

If you have an existing condition, such as heart disease or cancer, or if you take medication, it is a good idea to get a professional opinion if you start a new way of eating and experience any negative signs or symptoms.

Final thoughts

• A macrobiotic diet is a dietary approach that comes from Asian traditions that emphasize the consumption of mainly vegetable (vegetarian) proteins, low amounts of animal foods and fats, and a balance of different micro and macronutrients that support the energy balance of yin -yang in the body.

• Macrobiotics argue that foods that have different energy qualities and a primarily plant-based diet are good for health (especially the digestive system) and also good for the ecosystem.

• An emphasis on local, seasonal and fresh plant-based foods is believed to support agriculture, local farming, and mental well-being. It could also support heart health, promote longevity, and offer protection against cancer.

• Important practices when consuming macrobiotic foods include buying locally grown organic products, cooking often at home, avoiding packaged foods, eating fermented and raw foods, and limiting dairy and animal products.

• Although a macrobiotic diet has been shown to have anti-inflammatory effects, some concerns are that macrobiotic diets are high in salt but relatively low in protein, fruit antioxidants, vitamin D, calcium, and sometimes B vitamins.

We hope the article on the 5 benefits of a macrobiotic diet for health has been of help.

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Serious side effects of metoprolol

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  • Discover the serious side effects of metoprolol.
  • How does this medication work? What are its effects?
  • Metoprolol belongs to the class of medications called beta-blockers. Metoprolol is used to treat high blood pressure and prevent symptoms of certain types of angina ( chest pain). It is also used to reduce the risk of death immediately after a heart attack. It works by reducing the needs of the heart during exercise.
  • People who have had a heart attack take metoprolol to avoid having another heart attack. Metoprolol is often used in combination with other drugs that lower high blood pressure, such as diuretics (pills that increase urine output), when just one agent is not enough to control blood pressure.
  • This medicine is available under various brand names or in different formulations, or both. A specific brand of this medication may not be available in all forms and may not have been approved for all of the conditions discussed here. Also, some forms of this medicine may not be used for all of the conditions mentioned in this article.
  • Your doctor may have suggested this medication for a condition that is not listed in this Medication Information article. If you have not yet discussed this with your doctor, or if you are not sure why you are taking this medicine, consult your doctor. Do not stop taking this medicine without consulting your doctor first.
  • Do not give this medicine to anyone, even someone who has the same symptoms as yours. This medicine could harm people for whom it was not prescribed.
  • What forms does this medication come in?
  • Apo-Metoprolol
  • 25 mg
  • Each white, oval, scored tablet, engraved “ME” over “25” on one side and “APO” on the other, contains 25 mg of metoprolol tartrate. Nonmedicinal ingredients: colloidal silica dioxide, croscarmellose sodium, lactose monohydrate, magnesium stearate, and microcrystalline cellulose.
  • 50 mg
  • Each white, round, scored tablet, engraved “APO” over “M50”, contains 50 mg of metoprolol tartrate. Nonmedicinal ingredients: colloidal silica dioxide, croscarmellose sodium, lactose, magnesium stearate, and microcrystalline cellulose.
  • 100 mg
  • Each white, round, scored tablet, debossed with “APO” over “M100”, contains 100 mg of metoprolol tartrate. Nonmedicinal ingredients: colloidal silica dioxide, croscarmellose sodium, lactose, magnesium stearate, and microcrystalline cellulose.
  • Apo-Metoprolol (Type L)
  • 50 mg
  • Each pink, capsule-shaped, coated tablet, scored on one side and engraved “50” on the other, contains 50 mg of metoprolol. Nonmedicinal ingredients: carnauba wax, colloidal silica dioxide, croscarmellose sodium, D&C aluminum lake red No. 30, sun yellow aluminum lake, hydroxypropyl methylcellulose, lactose, magnesium stearate, microcrystalline cellulose, polyethylene glycol 3350, and sodium dioxide. titanium.
  • 100 mg
  • Each blue, capsule-shaped, coated tablet, scored on one side and engraved “100” on the other, contains 100 mg of metoprolol. Nonmedicinal ingredients: carnauba wax, colloidal silica dioxide, croscarmellose sodium, hydroxypropylmethylcellulose, indigotin aluminum lake (AD & C blue # 2), lactose, magnesium stearate, microcrystalline cellulose, polydextrose, polyethylene glycol 3350, and titanium dioxide.
  • How should this medication be used?
  • The usual maintenance dose of metoprolol ranges from 100 mg to 200 mg per day, however, this dose may be increased to 400 mg per day as needed to achieve symptom control. Immediate-release tablets are taken in 2 divided doses while slow-release tablets are taken once a day.
  • This medication should be taken soon after a meal, but try to take it at the same time every day.
  • Several factors can be taken into account in determining the dose a person needs: their weight, their health, and whether they are taking other medications. If your doctor has recommended a dose other than those listed here, do not change the way you are taking the medicine without consulting your doctor.
  • This medicine must be taken exactly as your doctor has told you. If you miss a dose, take the medicine as soon as you notice the missed dose and resume treatment as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your usual dosing schedule. Do not use a double dose to make up for a missed dose. If you are unsure of what to do after missing a dose, ask your doctor or pharmacist for advice.
  • Store this medication at room temperature, protect it from light and moisture, and keep it out of the reach of children.
  • Do not dispose of medicines in the wastewater (eg not in the sink or in the toilet bowl) or with the household garbage. Ask your pharmacist how to dispose of unused or expired medicines.
  • In which cases is this medication not recommended?
  • Do not use this medicine under the following circumstances:
  • a condition such as right ventricular failure caused by high blood pressure in the lungs;
  • is allergic to metoprolol or any of the ingredients of the medication
  • are allergic to other beta-blockers;
  • anesthesia caused by an agent having a depressant effect on the myocardium (eg ether);
  • a history of heart attack accompanied by:
  • a heart rate of fewer than 45 beats per minute,
  • severe heart block
  • very low blood pressure
  • moderate or severe heart failure.
  • slow heartbeat caused by problems with the heart rhythm;
  • severe heart block;
  • cardiogenic shock;
  • significant circulatory disorders;
  • proven heart failure;
  • the presence of asthma or other obstructive airway conditions (only when it comes to metoprolol in intravenous form);
  • a disorder referred to as “sinus dysfunction syndrome”;
  • have untreated pheochromocytoma (a tumor of the adrenal glands).
  • What are the possible side effects of metoprolol
  • Many medications can cause side effects. A side effect is an unwanted response to a drug when taken in normal doses. It can be mild or severe, temporary or permanent. The side effects listed below are not experienced by everyone who takes this medication. If you are concerned about side effects, discuss the risks and benefits of this medication with your doctor.
  • At least 1% of people taking this medicine reported the following side effects. Many of these side effects can be managed and a few may go away on their own over time.
  • Consult your doctor if you experience these side effects and if they are serious or bothersome. Your pharmacist may be able to give you advice on what to do if these side effects appear:
  • changes in libido or sexual ability;
  • constipation;
  • diarrhea;
  • pain or discomfort in the abdomen;
  • dizziness or light-headedness when changing from sitting or lying down to standin
  • fatigue or unusual weakness brought on by activity;
  • fatigue;
  • headaches;
  • nausea;
  • hair loss;
  • weight gain;
  • dreams giving a powerful sensation;
  • dry mouth;
  • increased sensitivity of the skin to solar radiation;
  • increased sweating;
  • sleep disturbances;
  • vomitings.
  • Most of the side effects listed below do not happen very often, but they could cause serious problems if you do not see your doctor or receive medical attention.
  • Check with your doctor as soon as possible if any of the following side effects occur:
  • slow heartbeat (especially less than 40 beats per minute);
  • hearing changes;
  • confusion;
  • difficulty breathing or wheezing;
  • back or joint pain;
  • chest pain;
  • hallucinations (the perception of phenomena that do not exist);
  • tingling in the arms and legs.
  • a feeling of coldness in the hands and feet;
  • signs of depression (eg, lack of concentration, weight fluctuations, trouble sleeping, indifference to many activities, thoughts of suicide);
  • signs of certain heart problems (e.g., increased or irregular heartbeat or pulse, chest pain, difficulty breathing, excessive fatigue, swelling of the feet, ankles, or part lower legs);
  • signs of certain kidney problems (eg increased or reduced urine production, itching, nausea, vomiting, rash);
  • signs of a bleeding disorder (e.g. unusual nosebleeds, bruising, blood in urine, cough with bloody sputum, bleeding gums, cuts that keep bleeding) ;
  • signs of liver problems (eg, nausea, vomiting, diarrhea, loss of appetite, weight loss, yellowing of the skin or whites of the eyes, dark urine, pale stools );
  • a flare-up of psoriasis (eg, red spots the size of a pinhead on the skin; red, scaly, or crusty skin);
  • a feeling of numbness or tingling in the extremities;
  • symptoms of low blood pressure (eg, dizziness, fatigue);
  • vision changes (eg blurred vision, dry eye, eye pain).
  • Stop taking the drug and seek immediate medical attention if there is a response such as :
  • coldness, discoloration, or pain in the fingers or toes;
  • symptoms of a serious allergic reaction (such as swelling of the face or swelling of the throat, hives, or difficulty breathing).
  • Some people may experience side effects other than those listed. See your doctor if you notice any symptom that worries you while you are using this medicine.
  • Are there other precautions or warnings?
  • Before using any medication, be sure to tell your doctor about any medical conditions or allergies you may have, the medications you are using, and any other important facts about your health. Women should mention if they are pregnant or breastfeeding. These factors could influence how you should use this medicine.
  • Respiratory disorders: In general, people with asthma, and certain other lung problems, should generally avoid taking beta-blockers such as metoprolol, as they can cause breathing difficulties. If you have breathing problems, and your doctor has prescribed metoprolol for you, it is probably in lower doses, and they will monitor you regularly while you are using this medicine. If you have breathing problems, talk to your doctor about how this medicine may affect your condition, how your condition affects the administration and effectiveness of this medicine, and whether medical supervision is needed. specific.
  • Severe allergies: If you have allergies severe enough to cause anaphylaxis (a severe allergic reaction in which swelling of the face, lips, and throat makes it very difficult to breathe), talk to your doctor about what to do next. take if you have an allergic reaction. the use of metoprolol may make it more difficult to treat severe allergic reactions with epinephrine.
  • Stopping the drug: People with heart disease who suddenly stop taking this drug may experience chest pain, irregular heartbeat, or a heart attack. If you have heart disease, do not stop taking this medication without consulting your doctor first. When this medication is to be stopped, it should be done gradually, under the supervision of your doctor.
  • Diabetes: The signs associated with low blood sugar may be more difficult to see while you are taking metoprolol. People with diabetes may have a harder time regulating their blood sugar levels when taking this medicine. If you have diabetes, discuss with your doctor how this medication may affect your condition, how your condition affects the administration and effectiveness of this medicine, and whether medical supervision is needed. specific. You will be kept under medical supervision while taking this medicine and your doctor may need to adjust your doses of diabetes medicine.
  • Dizziness or syncope: Metoprolol may cause side effects, including dizziness or fainting, soon after starting treatment. Do not drive a vehicle or do other potentially dangerous tasks until you know how this medicine works for you.
  • Hyperthyroidism (high level of thyroid hormones): Metoprolol may mask the symptoms of a person with hyperthyroidism (high level of thyroid hormones).
  • If you have hyperthyroidism, discuss with your doctor how this medication may affect your condition, how your condition affects the administration and effectiveness of this medicine, and whether it is appropriate to have it. specific medical surveillance. Stopping the medication suddenly could make this condition worse.
  • Liver function: Liver disease or reduced liver function can cause this drug to build up in the body, causing side effects. If you have liver problems, talk to your doctor about how this medicine may affect your condition, how your condition affects the administration and effectiveness of this medicine, and whether medical supervision is needed. specific. Your doctor will monitor your liver function with regular blood tests while you are taking this medicine.
  • If you notice symptoms of liver problems such as fatigue, feeling unwell, loss of appetite, nausea, yellowing of the skin or whites of the eyes, dark urine, pale stools, abdominal pain, or swelling and itching of the skin, contact your doctor immediately.
  • Kidney function: Taking metoprolol may affect kidney function. Your doctor will take this into account in his monitoring and will adjust your dose as needed. If you have reduced kidney function or kidney disease, talk to your doctor about how this medicine may affect your condition, how your condition affects the administration, and how well this medicine works. , and the relevance of specific medical surveillance. If you notice swelling in your hands, feet, or face, an increase in your blood pressure, unusual muscle cramps, or a dark appearance of your urine, this medicine may be interfering with the proper function of your blood. kidneys.
  • If you notice any of these symptoms, contact your doctor as soon as possible.
  • Heart disease: Beta-blockers like metoprolol can worsen already present heart failure. It is essential to use metoprolol as prescribed by your doctor to reduce this risk. If you have a history of heart disease, discuss with your doctor how this medication may affect your condition, how your condition affects the administration and effectiveness of this medicine, and whether it is appropriate to use it. specific medical surveillance.
  • Pheochromocytoma: This medicine may worsen the symptoms of pheochromocytoma (a tumor of the adrenal gland) if taken alone Talk to your doctor about how this medicine might affect your condition, how your condition affects your condition. administration and efficacy of this medicinal product, and the relevance of specific medical supervision.
  • Surgery: If you are about to have surgery, tell all healthcare professionals who treat you that you are using metoprolol.
  • Pregnancy: This medication should not be used during pregnancy unless the benefits outweigh the risks. If pregnancy occurs while you are using this medicine, contact your doctor immediately.
  • Breast-feeding: This medicine passes into breast milk. If you use metoprolol while you are breastfeeding your baby may feel the effects. Check with your doctor to see if you should continue breastfeeding.
  • Children: The safety and effectiveness of this medicine have not been established in children
  • Seniors: Normal doses of metoprolol for adults may lower blood pressure more than expected. Lower doses may be necessary for the elderly.
  • Can other agents interact with this medication?
  • There may be an interaction between metoprolol and any of the following:
  • abiraterone acetate;
  • acetylcholine;
  • anesthetic agents;
  • alpha agonists (eg, clonidine, methyldopa);
  • alcohol;
  • aldesleukin;
  • aliskiren;
  • alpha1-blockers (eg doxazosin, prazosin, tamsulosin);
  • amifostine;
  • amiodarone;
  • amphetamines (eg, dextroamphetamine, lisdexamfetamine);
  • serotonin antagonists (antiemetic drugs; eg dolasetron, granisetron, ondansetron);
  • tricyclic antidepressants (eg amitriptyline, clomipramine, desipramine, trimipramine);
  • antihistamines (eg, cetirizine, doxylamine, diphenhydramine, hydroxyzine, loratadine, diphenhydramine);
  • nonsteroidal anti-inflammatory drugs (NSAIDs) eg. ibuprofen, indomethacin, naproxen);
  • antimalarials (e.g. chloroquine, hydroxychloroquine, mefloquine, quinine);
  • antipsychotics (eg, chlorpromazine, clozapine, haloperidol, olanzapine, quetiapine, risperidone);
  • asunaprevir;
  • atomoxetine;
  • other beta-blockers (eg, atenolol, pindolol, propranolol);
  • azelastine;
  • barbiturates (eg, butalbital, pentobarbital, phenobarbital);
  • beta-agonists (anti-asthma medicines, eg salbutamol, salmeterol, formoterol);
  • calcium channel blockers (eg, verapamil, diltiazem, nifedipine, amlodipine);
  • angiotensin II receptor blockers (ARBs) eg. irbesartan, losartan);
  • bortezomib;
  • brimonidine;
  • buprenorphine;
  • bupropion;
  • celecoxib;
  • ceritinib;
  • milk thistle;
  • cholecalciferol;
  • cimetidine;
  • cinacalcet;
  • clobazam;
  • clotrimazole;
  • cobicistat;
  • cocaine;
  • cyproterone;
  • darifenacin;
  • delavirdine;
  • rye ergot derivatives (eg bromocriptine, ergotamine, methylergonovine);
  • nitro derivatives (eg nitroglycerin, isosorbide dinitrate, isosorbide mononitrate);
  • dextromethorphan;
  • digoxin;
  • dipyridamole;
  • disopyramide;
  • disulfiram;
  • diuretics (pills to remove water; eg furosemide, hydrochlorothiazide);
  • donepezil;
  • doxorubicin;
  • dronedarone;
  • entacapone;
  • epinephrine;
  • grass pollen allergen extract;
  • fentanyl;
  • fingolimod;
  • flecainide;
  • floctafenine;
  • galantamine;
  • ginger;
  • ginseng;
  • guanfacine;
  • imatinib;
  • phosphodiesterase type 5 inhibitors (eg, sildenafil, tadalafil);
  • proton pump inhibitors (eg, lansoprazole, omeprazole, rabeprazole);
  • Angiotensin-Converting Enzyme Inhibitors (ACEIs) eg. captopril, ramipril);
  • selective serotonin reuptake inhibitors (eg fluoxetine, paroxetine, sertraline);
  • selective serotonin-norepinephrine reuptake inhibitors or SNRIs (eg, desvenlafaxine, duloxetine, venlafaxine);
  • insulin;
  • isoniazid;
  • ketoconazole;
  • lacosamide;
  • lanreotide;
  • levodopa;
  • lidocaine;
  • lomustine;
  • cholesterol “statin” drugs (eg pravastatin, simvastatin);
  • methacholine;
  • methadone;
  • methimazole;
  • methoxsalen;
  • methylphenidate;
  • metoclopramide;
  • midodrine;
  • mifepristone;
  • mirabegron;
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  • moclobemide;
  • nefazodone;
  • nevirapine;
  • nilotinib;
  • noradrenaline;
  • octreotide;
  • orphenadrine;
  • oxybutynin;
  • pasireotide;
  • pazopanib;
  • peginterferon alfa-2b;
  • pentoxifylline;
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  • sodium phenylbutyrate;
  • pilocarpine;
  • pimozide;
  • praziquantel;
  • propafenone;
  • quinidine;
  • quinine;
  • ranitidine;
  • regorafenib;
  • rifabutin;
  • rifampin;
  • rituximab;
  • rivastigmine;
  • ropinirole;
  • sulfonylureas (eg gliclazide, glyburide, tolbutamide);
  • temsirolimus;
  • terbinafine;
  • theophyllines (eg aminophylline, oxtriphylline, theophylline);
  • ticagrelor;
  • ticlopidine;
  • tizanidine;
  • tofacitinib;
  • tolcapone;
  • tranylcypromine;
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  • yohimbine.
  • If you are taking any of the above medicines, please tell your doctor or pharmacist.  In your case, your doctor may ask you to:
  • stop taking any of the medications;
  • replace one of the drugs with another;
  • change the way you take one or both of the medicines.
  • do not change anything at all.
  • Interference of one medicine with another does not always mean that you stop taking one of them. Ask your doctor what to do with drug interactions.
  • Drugs other than those listed above may interact with this drug. Tell your doctor everything you take, whether it is prescription or over-the-counter drugs and herbal remedies. Do not forget to mention any supplements you take. If you consume caffeine, alcohol, nicotine, or street drugs, you should tell your prescribing doctor since these substances can affect the way many drugs work
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Side effects of too much cinnamon

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