Categories: Medicinal plants

Cascara sagrada: origin, benefits and possible risks

Published by

Cascara sagrada is a popular remedy to combat constipation. However, there are some concerns about its use. Find out everything about this plant.

Cascara sagrada, scientifically named Rhamnus purshiana,  is a shrub native to temperate North America. It has elliptical leaves, little toothed, that measure between 4 and 8 centimeters. Cascara sagrada: origin, benefits and possible risks


In addition, the tree reaches between 6 and 12 meters in height. Although it blooms and produces black drupe-shaped fruits, its bark is often used, which concentrates on medicinal substances.

In particular, it is known as a natural laxative, since it promotes intestinal motility to facilitate the evacuation of stool.

Still, its use is not approved by the United States Food and Drug Administration (FDA), which has some warnings about its possible risks. Do you want to know more about it?

Benefits of Cascara sagrada

Cascara sagrada is also known as “California sea buckthorn,” “sacred bark,” “bearberry,” or “yellow bark.” Since ancient times, the natives have used the bark of this tree for medicinal purposes, especially for the relief of digestive disorders such as constipation.


In fact, in the 1890s, the United States Food and Drug Administration (FDA) approved its initial use as an over-the-counter laxative.

However, this approval was withdrawn in 2002, given the lack of evidence on its safety and efficacy.

That said, it is important to note that there are not enough scientific studies on the properties and effects of cascara sagrada.

A review released through Phytotherapy Research details that emodin, an anthraquinone present in the plant, is behind its laxative effect.

This substance is responsible for inhibiting the absorption of water and electrolytes in the intestines.

Thus, the volume of stool increases, as does the pressure within the intestine.


The result of this process is the stimulation of peristalsis, which allows an optimal evacuation of feces.

However, the plant has been classified as a “stimulating laxative” and its effect is milder than other plants such as senna.

Even its mechanism is different from options such as psyllium since the latter creates a kind of gel that facilitates the elimination of waste retained in the intestine.

However, keep in mind that it is not currently an FDA-approved treatment to relieve constipation.

Still, it is available as a herbal dietary supplement or as an ingredient in prescription laxatives. It is estimated that it induces evacuation about 8 or 12 hours after consumption.

Natural options for constipation are not always authorized for use by competent bodies, as is the case with cascara sagrada.


Possible risks and contraindications

To calm constipation, this plant should be used only occasionally and in the short term. Its use is estimated to be safe and well-tolerated in most healthy adults. Still, some may experience abdominal pain or cramps when ingesting the remedy.

The most serious problems arise from the excessive consumption of cascara sagrada.

The studies determined that anthraquinone is harmful when ingested in quantities exaggerated.

It is also believed to cause melanosis coli, an abnormal blackish-brown color located in the colon.

If consumed for one or two weeks, it causes a significant loss of electrolytes that leads to a state of dehydration. Consequently, the following symptoms are also possible:

Severe nausea


Feeling of weakness or fatigue.



Muscle spasms.

Heart rhythm disturbances.

Numbness or tingling in the extremities.

Decreased urine output



Rebound constipation.

Due to the lack of scientific studies, it is not known if it is safe in certain populations with special characteristics. Therefore, it is contraindicated in the following cases:

Pregnancy and breastfeeding.


Patients with diverticular disease, ulcerative colitis, Crohn’s disease, or severe hemorrhoids.


People with cardiovascular diseases.

Severe anemia

Recent colon surgery.

Gastrointestinal cancer patients.

People with liver or kidney disease.

Suspicion of appendicitis.


The simultaneous consumption of cascara sagrada with the following medications is not recommended :

Cardiac glycosides, such as digoxin, digitoxin, and digitonin.

Corticosteroid drugs.

Dehydration pictures present confusion, tiredness, and fatigue. These are some of the side effects of cascara sagrada.

Dosage and mode of consumption

To date, a recommended dose for ingesting cascara sagrada has not been specified. It can vary according to the age, weight, and health of the person.

Therefore, it is essential to follow the supplement manufacturer’s recommendations. The plant is available in the form of powder, capsules, tinctures, and teas. It should not be used for more than 3 days.


What should you remember about cascara sagrada?

You will likely come across cascara sagrada supplements when looking for complementary constipation remedies.

Still, you should know that it is not a first-line treatment for this disease. It must be used with great caution, due to the risks involved.

If you choose to consume it, you should not exceed the dose suggested by the manufacturer or prolong your intake for many days.

If possible, consult your doctor to find other alternatives


Sponsored links
Published by

Recent Posts

  • Weight loss

Chaz Bono weight loss 2022

Discover Chaz Bono weight loss secret 2022. Chaz Salvatore Bono, is an American writer, musician,… Read More

3 days ago
  • Nuts

25 benefits of tiger nuts and side effects

Discover the 25 shocking health benefits of tiger nuts. Tiger nuts are also known as… Read More

3 days ago
  • Fruits

14 Benefits of boiled apple water and side effects

Discover the 14 incredible health benefits of boiled apple water and side effects. Some people… Read More

3 days ago
  • Tea

15 Benefits of lipton tea and side effects

Discover the 15 shocking health benefits of drinking lipton green tea and side effects. You… Read More

3 days ago
  • Medicinal plants

Benefits of kalanchoe pinnata and side effects

Discover the 15 Amazing Health Benefits of Kalanchoe pinnata and side effects. Among the health… Read More

3 days ago
  • Articles

6 Benefits of tejocote root and side effects

Discover the 6 Benefits of tejocote root and side effects. In recent times, natural alternatives… Read More

3 days ago