Health
Benefits of hyaluronic acid for acne
Discover the benefits of hyaluronic acid for acne.
In most acne scars there is a loss of skin volume ( atrophy ), which gives the area where they form a depressed or “engraved” appearance.
This atrophy is the product of a lack of hyaluronic acid and collagen in the dermis, the intermediate part of the skin, responsible for giving the turgidity, volume, and elasticity of healthy skin.
Methods of treatment
There are different methods to treat atrophic scars, which we could classify into two different groups according to their speed of action:
· Immediate effect. They are called fillers, biocompatible substances that can be injected into the skin to give volume to areas that have lost it.
Among them, those of hyaluronic acid, polylactic acid, or calcium hydroxyapatite stand out among others. Its turgid effect is immediate, filling cavities, furrows, and atrophic areas of the skin with very natural results. The duration of these materials is limited, so periodically (every 6 – 18 months ) it is common to practice a new session.
· Delayed effect. It implies that they promote the synthesis of collagen and ground substance of the dermis. It is worth mentioning the fractional lasers (ablative or non-ablative) and the intermediate and deep peels.
The main advantage of these methods is that their effect is permanent once the optimal point of improvement has been reached, which is not immediate but after practicing several sessions of the procedure.
Hyaluronic acid is indicated in the treatment of atrophic, depressed, and ice-pick acne scars. There are different densities of hyaluronic acid, designed to treat different forms of atrophy or loss of volume.
For the treatment of moderate or ice pick acne scars, it is useful to use low and intermediate densities; and to recover a large volume in especially atrophic areas, it is possible to use higher densities to cover the maximum repertoire of defects.
The main advantages of using hyaluronic acid lie in its immediate action, its durability, its biocompatibility, and its minimal allergenic potential. This molecule can fill in atrophic scars, providing optimal volume immediately and in the short term, promoting collagen synthesis in the long run.
In this way, the irregularity on the surface of the skin is substantially reduced after the application of hyaluronic acid, improving the overall appearance of the skin in the treated area.
Another positive aspect of using hyaluronic acid is that it usually only requires a single application session. Likewise, fillers are one of the best tolerated aesthetic procedures since they have a minimal rate of adverse effects and the pain caused is minimal if a precise technique is followed. Slight erythema (redness) that lasts 2-4 hours after the procedure is common and can be reduced with the application of cold compresses.
According to studies published by Halachmi et al, the satisfaction rate and results in patients with atrophic acne scars and ice pick treated with hyaluronic acid are excellent.
The only limiting aspect of hyaluronic acid fillers is their duration. This molecule is naturally degraded in the skin, its effect persisting for 6-18 months depending on the density of hyaluronic acid used and the indication for which it has been applied.
Specifically, for acne scars, the duration of hyaluronic acid is the maximum possible, since it is retained within the fibrosis that partitions the scars. It should be remembered that, in the long term, this molecule favors the synthesis of collagen, so that the perceptible effect is progressively more durable as different sessions are carried out.
FREQUENT QUESTIONS
What is the main indication of hyaluronic acid in acne scars?
Its main effect is to fill in depressed scars and regularize the appearance of the skin surface.
When is the effect of hyaluronic acid noticeable?
The effect of hyaluronic acid is immediate and noticeable at the end of its application. Over a week or so, the hyaluronic acid settles in the applied area and the surface where it has been applied progressively becomes even more regular.
How is hyaluronic acid applied?
The procedure is performed in the Dermatology consultation through microinjections applied under the scars to be treated. An anesthetic cream is usually used before the session and it is very tolerable, with minimal discomfort.
How many hyaluronic acid sessions are needed to treat facial acne scars?
In general, if they are not very deep or extensive, one is enough.
How is the face after doing the filling session?
The corrective effect of hyaluronic acid is immediate. At the end of the session, most atrophic and depressed scars have recovered all or part of their lost volume. Immediately after the session, it is usual to see some redness in the treated areas and slight swelling, which usually lasts between 2-4 hours.
It is possible, although infrequent, that during the procedure a minimal punctual hematoma may appear in an injection area, which will disappear spontaneously over a week or so.
Is it a painful procedure?
Filling with hyaluronic acid after application of anesthetic cream is one of the most well-tolerated and appreciated aesthetic procedures, with an excellent satisfaction rate for the patient.
Can fillers be combined with other acne scar treatments?
Yes. They can be used concomitantly with ablative/non-ablative peels or lasers, or even botulinum toxin if desired. It is recommended, yes, to carry them out in different sessions.
Is the effect of hyaluronic acid definitive?
No. Although with each session there is a certain accumulation of the effect due to the collagen synthesis promoted by hyaluronic acid, it is advisable to perform a filler every 6-18 months depending on the indication and the area to be treated.
Health
14 Benefits of Oolong tea and side effects Table of Contents
Health
Contraindications of drinking green tea
Discover the contraindications of drinking green tea.
Drinking green tea in excess can cause some harmful side effects for the body, which are necessary to know
Green tea is one of the most popular in the world. In addition to having a characteristic flavor, its different properties make it a highly beneficial drink for health, mainly due to its antioxidant power. However, its consumption also includes a series of contraindications
Among the benefits of green tea highlights its ability to improve memory, helps lose body fat, increases physical performance, is stimulating, can prevent different types of cancer, and even reduce the risk of cardiovascular diseases.
Among all the types of green tea that exist, matcha stands out, a tea of oriental origin with important properties for health and that stands out for its powder composition. In recent years it has become the travel companion of celebrities, athletes, and famous people.
Contraindications of drinking green tea
Many people have incorporated green tea into their day-to-day. The truth is that it is a great choice since it can provide energy to face the workday, accelerate the metabolism, and can even help improve mood.
However, like any food, the consumption of green tea carries a series of contraindications that it is necessary to know.
Thus, from ‘Todo Disca’ we are going to expose some of the negative effects that the ingestion of this type of infusions can produce.
In this sense, researchers from the National Institute of Health of the United States affirm that the consumption of green tea mixed with different medications, such as contraceptive pills, antibiotics, stimulants, or alcohol can be harmful to health.
And these are some of the side effects that excess green tea consumption can generate for the body:
1. Irritability: Some people feel some discomfort at the time of their intake. That is to say, it produces an effect contrary to the one they seek at first.
2. Insomnia: Green tea can cause sleep problems for many people. And is that it is a stimulating drink that contains some doses of caffeine, although in a lower proportion than traditional coffee.
3. Dizziness and nausea: This infusion can be heavy for delicate stomachs and generate some type of gastrointestinal discomfort. Therefore, it is not advisable to take on an empty stomach.
4. Palpitations: Due to its stimulating characteristics, it can sometimes cause palpitations. Along these lines, experts recommend reading the indications and ingredients of all types of tea.
5. Disadvantages during pregnancy: Green tea is rich in tannins, so it can reduce the absorption of folic acid and iron. Due to this, this drink is not recommended for pregnant or lactating women.
Generally, green tea is an infusion with excellent health properties. In this way, moderate consumption usually brings different benefits to the body.
However, it is advisable to take these contraindications into account, and if you feel any side effects, see a medical specialist.
Through the following link, you will be able to know the contraindications to drink matcha tea, a variety of oriental origin widely established in Europe and whose consumption has become popular in recent years
Health
Contraindications and side effects of Trazodone
Discover the Contraindications and side effects of Trazodone.
Trazodone is used in a wide variety of disorders, although it is an antidepressant.
Being depression one of the most prevalent mental disorders worldwide and one of the major causes of disability, its treatment is a matter that the scientific community has taken into account for many years.
The suffering it generates requires sometimes immediate attention since it is one of the disorders with the highest risk of suicide and that generates the most pain both for the person and for those around him.
The treatment of depression is carried out from different areas, one of them being psychopharmacology.
One of the drugs used in the treatment of depression is trazodone, which we are going to talk about in this article.
Trazodone: what type of substance is it?
Trazodone is a psychotropic drug classified within antidepressants, substances that generate a neurochemical change at the brain level, causing alterations in the levels of certain neurotransmitters, specifically serotonin.
Among antidepressants, it is part and is the main representative of the group of serotonin-2A antagonists and reuptake inhibitors or SARIs, a type of atypical antidepressant.
This drug was designed in Italy in 1966 under the assumption that depression could be based on the existence of low thresholds regarding the perception of pain and suffering, being the product of the lack of integration of aversive experiences.
Trazodone has proven to be an efficient and effective drug in the treatment of depression, reducing passivity and inactivity, as well as the discomfort and suffering associated with said ailment, and facilitating an increase in mood.
However, in addition to this, it also has an anxiolytic and tranquilizing action.
This substance is considered a second-generation antidepressant, along with specific serotonin reuptake inhibitors (SSRIs), with which it shares part of its mechanism of action, and different dual antidepressants.
Trazodone is sometimes considered to be dual as it has two different effects, although they focus on the same neurotransmission system, compared to the rest, and in addition to an antidepressant effect, it also has calming effects.
How does it work? Mechanism of action of the drug
As we have indicated previously, trazodone is classified as SARI, having a somewhat special mechanism of action among the rest of antidepressants.
Trazodone acts at the serotonergic system level (like most antidepressants) in two specific ways.
In the first place, this substance produces a blockage of brain serotonin reuptake, in such a way that said neurotransmitter remains in the synaptic space for a longer time.
This supposes that it has an agonist effect on the synthesis and maintenance of serotonin at the brain level, it increases its levels (which are decreased during the depression and this is something that correlates with the decrease in the mood).
The aforementioned mechanism of action is the one used by SSRIs, which is why these and trazodone are related and sometimes the latter is included among the first.
However, trazodone has a second effect that differentiates it from other drugs, and that seems contrary to the previous mechanism of action.
And it is also that it acts as an antagonist of serotonin 5-HT2A receptors, preventing or hindering these receptors from being activated.
This second aspect is what makes trazodone have a slightly different profile and effects than other antidepressants.
Regarding its interaction with other neurotransmitter systems, it does not present great anticholinergic effects, something that has made this drug a better option than tricyclics (although the doses must also be regulated) in patients with cerebrovascular and cardiac pathology and dementias.
However, it must be taken into account that it can generate arrhythmias.
It also has a minor effect on the adrenergic (blocking some receptors) and histaminergic systems, something that can lead to the generation of side effects.
Main indications
The main indication for trazodone is obviously, as an antidepressant that it is, major depression. Its effectiveness is also high in those depressions that appear together with anxiety symptoms.
Its clinical utility has also been observed in other disorders in which there are components of anxiety or that are based on it, such as generalized anxiety disorder, Obsessive-Compulsive Disorder, or bulimia.
In addition to this, it has also been observed to be useful for the treatment of substance addictions, being a good alternative for patients with withdrawal syndrome to benzodiazepines, and in the treatment of alcoholism (including the presence of delirium tremens).
Another of its indications is insomnia, which is effectively reduced by increasing sleep time without greatly affecting the deep sleep phase.
Although in general, most antidepressants can have the presence of erectile dysfunction or ejaculation problems as a side effect, this effect does not usually occur in trazodone, which seems to generate an increase in libido and is even used as a treatment indicated in erectile dysfunction.
Finally, trazodone has been applied (largely for its relaxing properties) in some cases of schizophrenia, motor problems such as Gilles de la Tourette syndrome, the presence of manic episodes in bipolar disorder, and the behavioral disorders of Alzheimer’s. although a greater amount of study is required regarding the latter.
On a medical level, it has also been used as a sedative in HIV-infected patients and diabetic neuropathies, as well as in other disorders that cause pain such as fibromyalgia. It has a very slight effect at the level of muscle relaxant.
Side effects and contraindications
Trazodone is a very useful drug that has been used in multiple pathologies and disorders, both mental and medical.
However, it can have undesirable consequences in the form of side effects and is even contraindicated in some situations and pathologies.
Secondary symptoms, sedation, and fatigue, the presence of headaches, nausea, and vomiting, gastric disturbances (diarrhea or constipation), appetite disturbances, sweating, tremors (which may lead to seizures in some cases), are common. ringing, numbness, and vision problems.
In some cases, it can also cause chest and muscle pain, altered consciousness, breathing problems, and arrhythmias. Like other antidepressants, trazodone can also contribute to the genesis of suicidal ideation in the first moments of use.
Although, unlike other antidepressants, it does not seem to generate contributes to improving cases of erectile dysfunction or ejaculatory problems, the use of trazodone has been observed and associated with the appearance of priapism, erections that do not disappear on their own. alone and that cause pain to those who suffer from them (which may require urgent and even surgical treatment).
Although it is sometimes used in dementias and has a lower risk than tricyclics of generating heart problems, it requires a high degree of caution in its use and dosage carefully prescribed by the doctor, since it can generate arrhythmias.
It is contraindicated in patients who have just suffered a heart attack, as well as in those with liver or kidney disease.
Caution should be exercised in subjects with bipolarity because if the medication is not regulated, the consumption of trazodone can cause a shift from depressive to manic phase.
It is also contraindicated in people who have suffered from priapism or have Peyronie’s disease.
Finally, it must be taken into account that trazodone can be excreted in breast milk and transmitted through the placenta so that pregnant and lactating women have contraindicated its use.
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