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11 Benefits of pepper and side effects

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Discover the 11 shocking health benefits of pepper and side effects.

The bell pepper (Capsicum) an ancestral spice, is a diverse and spicy edible fruit of any of the varieties within the Capsicum genus.

With the well-known popular use of the pepper, multiculturally, and for generations around the world, interest is developing in knowing the medicinal benefits of this natural plant food and culinary spices.

Many people are familiar with the use of bell peppers in the preparation of spicy foods, but what is it that makes them spicy?

The answer is capsaicin, an odorless and tasteless phytochemical that produces the heat in bell peppers.

With the varieties of peppers available, it is important to know that the capsaicin content of each type varies and that it is possible to get less heat and still receive the health benefits of the active ingredient capsaicin from chili peppers.

Capsaicin is found in the fleshy membrane of sweet and hot peppers and a higher concentration in the seeds.

This natural fruit can be used fresh or dried as a culinary spice, added to teas, or taken in capsules to reap its medicinal benefits.

The health benefits of pepper include relief from stomach problems, back pain, muscle spasms, headaches, cancer, aging skin, peptic ulcers, menopausal problems, lower risk of cardiovascular disease and diabetes.

It has anti-inflammatory and analgesic properties, and it can also provide relief from arthritis-related pain. Capsicum also helps with fibromyalgia and psoriasis

Nutrition facts of Capsicum

• The use of whole chili peppers of the genus Capsicum provides nutritional value, including high amounts of vitamin C and vitamin A.

• These vitamins are best obtained from fresh fruit.

• Chili peppers harvested when the color is red rather than orange or yellow have higher concentrations of these beneficial nutrients.

• Other beneficial bioactive components of bell pepper are the flavonoid content.

• Alkaloids and tannins are some of the other important bioactive compounds contained in it.

• Alkaloids work as anti-inflammatory, pain relievers, and antioxidant agents.

11 Health Benefits of Pepper

Adding capsicum to your daily diet can provide great health benefits against many ailments. Let’s see the benefits in detail:

1.- Benefits of pepper for inflammation

• The phytochemical constituents of bell pepper have been shown to produce an anti-inflammatory response that alleviates peripheral neurogenic pain related to Crohn’s disease, an inflammatory disease of the intestines.

• Another example of peripheral neurogenic inflammation in cutaneous pain of the skin.

• Pepper creams and balms are often applied by massaging topically onto the skincare to avoid open areas and mucous membranes.

• The burning effect of capsicum is felt when applied to the skin, which is caused by an inflammatory response from the peripheral nerve endings.

• But regular application attenuates sensory nerve endings and relieves chronic diabetic neurogenic pain.

• Some suggest that the anti-inflammatory effect of bell pepper may also help ease arthritis-related pain.

• Its cream can be used as an option to treat this disease and many others.

2.- Benefits of pepper for stomach

• Capsicum contains tannins. Tannins are astringent and are often considered beneficial when treating gastrointestinal disorders such as diarrhea, dysentery, and other microbial disorders.

• Gastric mucilage works to protect the gastric lining and prevent the development of peptic ulcers.

• Studies suggest that it acts as a mucilage to increase gastric mucus production and help treat peptic ulcer disease.

• Taking capsicum can increase nasal drainage due to the presence of phytochemical capsaicin.

• Also, for this reason, it is beneficial to avoid touching your eyes or body mucus membranes when preparing capsicum peppers.

• In the same way, wash your hands thoroughly after preparation to avoid transferring volatile oils containing pepper to these sensitive areas.

3.- Benefits of pepper for cancer

• Another bioactive effect of the tannin contained in the pepper is in the prevention and treatment of cancer.

• Studies have shown that it has an inhibitory effect on many types of malignant cancers.

• These antitumor properties are most beneficial in treating lung, liver, and gastric cancers.

• The antioxidant effects of capsicum show a possibility of treatment for other types of cancer, such as hormone-related prostate cancer.

• The anti-cancer effect of pepper is determined by the bioactive ability of the phytochemical capsaicin to inhibit the growth of cancer cells.

• Capsaicin also destroys already damaged cell structures in the human body.

4.- Benefits of pepper for heart

• Studies on flavonoids have suggested that they are beneficial in preventing coronary heart disease.

• The pepper is both caloric and vasodilator.

• A suggested effect of the vasodilator properties of the pepper is the improvement of hypotension and the decrease of the heart rate.

• Vasodilation allows better blood flow resulting in better oxygenation of organ tissues.

• This is most likely due to tachykinins, a known bioactive ingredient in capsicum.

5.- Antioxidant agent

• Many of the bioactive compounds in bell pepper provide antioxidant effects.

• Enhanced vasodilation allows these antioxidant phytochemicals to circulate throughout the body.

• This allows you to protect and repair tissue and DNA damage.

6.- Benefits of pepper for diabetes

• With the worldwide prevalence of diabetes, the consideration of capsicum as a hypoglycemic drug has sparked research in this matter.

• Some studies have indicated, although it has not yet been concluded, that it can stimulate insulin production resulting in lower blood glucose.

• This would determine a possibility the pepper is beneficial in preventing the onset of type II diabetes and its possible complications.

• The hypoglycemic benefits of the pepper are more concentrated when it is green.

7.- Increases immunity

• The bell pepper contains vitamin C, which is valued as bioactive immune support phytochemical.

• Helps strengthen the immune system, repair damaged brain tissues, and reduce the risk of oxidative stress, pediatric asthma, and cancer.

• It also improves bone health.

8.- Treat fibromyalgia

• Many clinical trials show the efficacy of capsicum in treating fibromyalgia symptoms when applied topically.

• Those who use capsicum topically reported beneficial effects on improving sleep.

9.- Treat diabetic neuropathy

• One disease that often causes neurogenic pain is diabetes.

• Capsicum has been shown to have a beneficial effect on diabetic neuropathic pain when applied topically.

• It works to cushion the skin’s nerve endings and reduces pain.

10.- Benefits of pepper for Skin

• The vitamins in bell pepper have been shown to have an antioxidant effect on cell tissues, which can improve skin health and prevent aging.

11.- Relieves the symptoms of menopause

• Menopausal symptoms can also be alleviated by consuming fruits that contain flavonoids, such as chili peppers.

Uses of the pepper

• The pepper comes in dry form, as a spice like a chili pepper and paprika. The dried spice is used in many sauces or added to beverages such as tea.

Dried bell pepper can be found in whole dried bell peppers, as a single spice, or in dried spice mixes.

• As a more concentrated medication, bell pepper can be placed in a capsule for oral ingestion as a nutraceutical or applied topically to the skin as an analgesic and anti-inflammatory cream.

• With the availability of chili pepper in many markets, it should be considered that although the dried spice is convenient and effective in terms of its health benefits, eating fresh chili provides more benefits.

• As studies show bell pepper is beneficial as a daily health supplement.

The bell pepper is enjoyed by many as a daily food additive in cooking.

The culinary preparation of bell pepper can provide sufficient protection when consumed daily to have beneficial effects on certain chronic and potentially degenerative health conditions.

• The bioactive components in capsicum work together to improve blood flow, act as a cancer preventative and pain reliever, protect the gastric mucosa, and provide nutrients for a healthy lifestyle.

• Although all peppers contain vitamins and other beneficial bioactive components.

However, the color of the pepper determines the growth stage when it is harvested.

It also determines the concentration of vitamins and other beneficial phytochemicals.

In general, it can be said that, whether consumed dry or fresh, chili pepper is medicinal and beneficial to use in a daily diet as both a natural preventative and a treatment for many chronic conditions.

5 simple pepper recipes

A.- Fusilli with mushrooms and peppers

Ingredients (for 2 people)

• 200 grams of fusilli

• 100 grams of mushrooms

• 10 cherry tomatoes

• 1/2 green pepper and 1/2 red

• 1 clove garlic

• 1 lemon

• 2 tablespoons olive oil

• Parsley

• Thyme

• Salt

• Pepper

Preparation

• Wash the peppers, remove the seeds, and cut them into strips.

• Remove the stem from the mushrooms, clean them, run them under water, dry them with a clean cloth, and cut them into pieces.

• Wash the parsley, dry it with absorbent paper and chop it.

• Wash the tomatoes and cut them in half. Peel and mince the garlic clove.

• Wash the lemon, dry it and get a tablespoon of the zest from its skin into thin strips.

• Boil salted water and cook the pasta until al dente.

• Drain and reserve.

• In a very wide pan, heat 2 teaspoons of oil, sauté the minced garlic in it for 1 minute without letting it turn color.

• Add the mushrooms and cook for 2 more minutes. Add the peppers, the tomatoes and cook everything together for about 5 minutes.

• Season with salt and pepper, sprinkle with the chopped parsley, a little thyme, and mix.

• Add the pasta to the casserole with the grated lemon strips, sauté everything together for 2 minutes, and serve.

B.- Beef skewers with peppers

Ingredients for 4 people)

• 750 grams of beef tenderloin

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• 1 red, 1 green, and 1 yellow bell pepper

• 50 milliliters of oil

• 2 tablespoons minced thyme leaves

• Salt

• Black pepper

Preparation

• Cut the meat into 3-centimeter cubes and put it in a salad bowl. Sprinkle the thyme, season, and drizzle with the oil.

• Mix and marinate in the refrigerator for 30 minutes.

• Wash the peppers, remove the peduncle and seeds, and cut into squares.

• Thread the meat on the skewers and alternate it with the pepper; place in a large skillet to grill over high heat for 3 minutes on each side.

• Remove from the fire and serve.

C.- Chicken recipe with red and green peppers

Ingredients for 4 people)

• 500 grams of chicken

• 100 grams of onion

• 2 minced garlic

• 50 milliliters of soy sauce

• Basil

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• 100 grams of green peppers and 100 grams of red

• Olive oil

Process

• Cut the chicken into pieces of about 2 centimeters. You can use any part of the chicken from the breast to the thighs.

• In a bowl, place the chicken, the onion cut into fine julienne strips, the minced garlic, the soy sauce, and the basil and leave to marinate. Meanwhile, make the peppers.

• Clean and cut the peppers into strips lengthwise. In a skillet, sauté them over high heat for 30 seconds so that they are crisp. Reserve.

• In the same pan where you sautéed the peppers, cook the chicken with the rest of the marinated ingredients. Once the chicken is cooked add the peppers, mix and serve warm.

D.- Peppers stuffed with cheese and bacon

Ingredients

• 12 small green peppers

• 2 sheets of puff pastry

• 225 grams of cream cheese

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• 60 grams of smoked bacon

• 120 grams of cheddar cheese grated

• 2 eggs

Process

• Preheat the oven to 180ºC.

• Meanwhile, in a bowl, mix the cheddar cheese, cream cheese, and smoked bacon into pieces.

• Cut the puff pastry into squares of approximately 8 cm x 8 cm.

• Wash the peppers well, remove the seeds and the tail. Cut them in half. Choose small peppers to fit in the puff pastry (or cut larger pieces of puff pastry).

• Fill the peppers with the cheese mixture and smoked bacon. Wrap them with the puff pastry squares.

• Beat two eggs and bathe the puff pastry packets with this mixture. Cover well with the egg mixture.

• Bake for 20 minutes. Remove and serve hot.

E.- Pepper stuffed with ground meat

Ingredients for 4 people)

• 4 pieces of bell pepper

• 400 grams of ground beef

• 2 carrots

• 200 grams of peas

• 1 large potato

• ¼ onion

• 1 clove garlic

• 1 pinch of salt

• 1 pinch of pepper

• 2 tablespoons of oil

Process

• Chop the carrot and potato into small cubes. Once ready, place them in a saucepan with enough boiling water to cook them. Also, add the peas or peas and cook all together, adding a pinch of salt. Once the vegetables are cooked, remove them from the heat, drain, and reserve.

• In another deep saucepan adds the oil, heat over medium heat, and, once hot, add the chopped onion and garlic to fry. Add a taste of salt.

• Once the onion is transparent, add the ground beef to the saucepan and stir to incorporate it perfectly. Let it cook for approximately 15 minutes, stirring constantly so that it cooks evenly.

• Meanwhile, take the peppers and cut the top with the stem to form a kind of lid. Then devein the chiles and clean them very well inside. Reserve a moment.

• On the other hand, once the ground meat is cooked, add the vegetables and let the ingredients of the filling finish cooking altogether.

• When the ground beef and vegetables are done, stuff the peppers. To do this, take a little of the stew and completely cover the inside of the chili peppers.

• Once filled, place them on a baking sheet greased with a little butter. Put some string cheese on top, or any other type of cheese, add the caps so that they also cook on the side, not on top of the chilies, and bake the peppers stuffed with ground beef for 10 minutes at 170 ° C.

• After this time, the peppers stuffed with ground meat are ready to be enjoyed

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Serious side effects of metoprolol

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side effects of metoprolol
  • Discover the serious side effects of metoprolol.
  • How does this medication work? What are its effects?
  • Metoprolol belongs to the class of medications called beta-blockers. Metoprolol is used to treat high blood pressure and prevent symptoms of certain types of angina ( chest pain). It is also used to reduce the risk of death immediately after a heart attack. It works by reducing the needs of the heart during exercise.
  • People who have had a heart attack take metoprolol to avoid having another heart attack. Metoprolol is often used in combination with other drugs that lower high blood pressure, such as diuretics (pills that increase urine output), when just one agent is not enough to control blood pressure.
  • This medicine is available under various brand names or in different formulations, or both. A specific brand of this medication may not be available in all forms and may not have been approved for all of the conditions discussed here. Also, some forms of this medicine may not be used for all of the conditions mentioned in this article.
  • Your doctor may have suggested this medication for a condition that is not listed in this Medication Information article. If you have not yet discussed this with your doctor, or if you are not sure why you are taking this medicine, consult your doctor. Do not stop taking this medicine without consulting your doctor first.
  • Do not give this medicine to anyone, even someone who has the same symptoms as yours. This medicine could harm people for whom it was not prescribed.
  • What forms does this medication come in?
  • Apo-Metoprolol
  • 25 mg
  • Each white, oval, scored tablet, engraved “ME” over “25” on one side and “APO” on the other, contains 25 mg of metoprolol tartrate. Nonmedicinal ingredients: colloidal silica dioxide, croscarmellose sodium, lactose monohydrate, magnesium stearate, and microcrystalline cellulose.
  • 50 mg
  • Each white, round, scored tablet, engraved “APO” over “M50”, contains 50 mg of metoprolol tartrate. Nonmedicinal ingredients: colloidal silica dioxide, croscarmellose sodium, lactose, magnesium stearate, and microcrystalline cellulose.
  • 100 mg
  • Each white, round, scored tablet, debossed with “APO” over “M100”, contains 100 mg of metoprolol tartrate. Nonmedicinal ingredients: colloidal silica dioxide, croscarmellose sodium, lactose, magnesium stearate, and microcrystalline cellulose.
  • Apo-Metoprolol (Type L)
  • 50 mg
  • Each pink, capsule-shaped, coated tablet, scored on one side and engraved “50” on the other, contains 50 mg of metoprolol. Nonmedicinal ingredients: carnauba wax, colloidal silica dioxide, croscarmellose sodium, D&C aluminum lake red No. 30, sun yellow aluminum lake, hydroxypropyl methylcellulose, lactose, magnesium stearate, microcrystalline cellulose, polyethylene glycol 3350, and sodium dioxide. titanium.
  • 100 mg
  • Each blue, capsule-shaped, coated tablet, scored on one side and engraved “100” on the other, contains 100 mg of metoprolol. Nonmedicinal ingredients: carnauba wax, colloidal silica dioxide, croscarmellose sodium, hydroxypropylmethylcellulose, indigotin aluminum lake (AD & C blue # 2), lactose, magnesium stearate, microcrystalline cellulose, polydextrose, polyethylene glycol 3350, and titanium dioxide.
  • How should this medication be used?
  • The usual maintenance dose of metoprolol ranges from 100 mg to 200 mg per day, however, this dose may be increased to 400 mg per day as needed to achieve symptom control. Immediate-release tablets are taken in 2 divided doses while slow-release tablets are taken once a day.
  • This medication should be taken soon after a meal, but try to take it at the same time every day.
  • Several factors can be taken into account in determining the dose a person needs: their weight, their health, and whether they are taking other medications. If your doctor has recommended a dose other than those listed here, do not change the way you are taking the medicine without consulting your doctor.
  • This medicine must be taken exactly as your doctor has told you. If you miss a dose, take the medicine as soon as you notice the missed dose and resume treatment as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your usual dosing schedule. Do not use a double dose to make up for a missed dose. If you are unsure of what to do after missing a dose, ask your doctor or pharmacist for advice.
  • Store this medication at room temperature, protect it from light and moisture, and keep it out of the reach of children.
  • Do not dispose of medicines in the wastewater (eg not in the sink or in the toilet bowl) or with the household garbage. Ask your pharmacist how to dispose of unused or expired medicines.
  • In which cases is this medication not recommended?
  • Do not use this medicine under the following circumstances:
  • a condition such as right ventricular failure caused by high blood pressure in the lungs;
  • is allergic to metoprolol or any of the ingredients of the medication
  • are allergic to other beta-blockers;
  • anesthesia caused by an agent having a depressant effect on the myocardium (eg ether);
  • a history of heart attack accompanied by:
  • a heart rate of fewer than 45 beats per minute,
  • severe heart block
  • very low blood pressure
  • moderate or severe heart failure.
  • slow heartbeat caused by problems with the heart rhythm;
  • severe heart block;
  • cardiogenic shock;
  • significant circulatory disorders;
  • proven heart failure;
  • the presence of asthma or other obstructive airway conditions (only when it comes to metoprolol in intravenous form);
  • a disorder referred to as “sinus dysfunction syndrome”;
  • have untreated pheochromocytoma (a tumor of the adrenal glands).
  • What are the possible side effects of metoprolol
  • Many medications can cause side effects. A side effect is an unwanted response to a drug when taken in normal doses. It can be mild or severe, temporary or permanent. The side effects listed below are not experienced by everyone who takes this medication. If you are concerned about side effects, discuss the risks and benefits of this medication with your doctor.
  • At least 1% of people taking this medicine reported the following side effects. Many of these side effects can be managed and a few may go away on their own over time.
  • Consult your doctor if you experience these side effects and if they are serious or bothersome. Your pharmacist may be able to give you advice on what to do if these side effects appear:
  • changes in libido or sexual ability;
  • constipation;
  • diarrhea;
  • pain or discomfort in the abdomen;
  • dizziness or light-headedness when changing from sitting or lying down to standin
  • fatigue or unusual weakness brought on by activity;
  • fatigue;
  • headaches;
  • nausea;
  • hair loss;
  • weight gain;
  • dreams giving a powerful sensation;
  • dry mouth;
  • increased sensitivity of the skin to solar radiation;
  • increased sweating;
  • sleep disturbances;
  • vomitings.
  • Most of the side effects listed below do not happen very often, but they could cause serious problems if you do not see your doctor or receive medical attention.
  • Check with your doctor as soon as possible if any of the following side effects occur:
  • slow heartbeat (especially less than 40 beats per minute);
  • hearing changes;
  • confusion;
  • difficulty breathing or wheezing;
  • back or joint pain;
  • chest pain;
  • hallucinations (the perception of phenomena that do not exist);
  • tingling in the arms and legs.
  • a feeling of coldness in the hands and feet;
  • signs of depression (eg, lack of concentration, weight fluctuations, trouble sleeping, indifference to many activities, thoughts of suicide);
  • signs of certain heart problems (e.g., increased or irregular heartbeat or pulse, chest pain, difficulty breathing, excessive fatigue, swelling of the feet, ankles, or part lower legs);
  • signs of certain kidney problems (eg increased or reduced urine production, itching, nausea, vomiting, rash);
  • signs of a bleeding disorder (e.g. unusual nosebleeds, bruising, blood in urine, cough with bloody sputum, bleeding gums, cuts that keep bleeding) ;
  • signs of liver problems (eg, nausea, vomiting, diarrhea, loss of appetite, weight loss, yellowing of the skin or whites of the eyes, dark urine, pale stools );
  • a flare-up of psoriasis (eg, red spots the size of a pinhead on the skin; red, scaly, or crusty skin);
  • a feeling of numbness or tingling in the extremities;
  • symptoms of low blood pressure (eg, dizziness, fatigue);
  • vision changes (eg blurred vision, dry eye, eye pain).
  • Stop taking the drug and seek immediate medical attention if there is a response such as :
  • coldness, discoloration, or pain in the fingers or toes;
  • symptoms of a serious allergic reaction (such as swelling of the face or swelling of the throat, hives, or difficulty breathing).
  • Some people may experience side effects other than those listed. See your doctor if you notice any symptom that worries you while you are using this medicine.
  • Are there other precautions or warnings?
  • Before using any medication, be sure to tell your doctor about any medical conditions or allergies you may have, the medications you are using, and any other important facts about your health. Women should mention if they are pregnant or breastfeeding. These factors could influence how you should use this medicine.
  • Respiratory disorders: In general, people with asthma, and certain other lung problems, should generally avoid taking beta-blockers such as metoprolol, as they can cause breathing difficulties. If you have breathing problems, and your doctor has prescribed metoprolol for you, it is probably in lower doses, and they will monitor you regularly while you are using this medicine. If you have breathing problems, talk to your doctor about how this medicine may affect your condition, how your condition affects the administration and effectiveness of this medicine, and whether medical supervision is needed. specific.
  • Severe allergies: If you have allergies severe enough to cause anaphylaxis (a severe allergic reaction in which swelling of the face, lips, and throat makes it very difficult to breathe), talk to your doctor about what to do next. take if you have an allergic reaction. the use of metoprolol may make it more difficult to treat severe allergic reactions with epinephrine.
  • Stopping the drug: People with heart disease who suddenly stop taking this drug may experience chest pain, irregular heartbeat, or a heart attack. If you have heart disease, do not stop taking this medication without consulting your doctor first. When this medication is to be stopped, it should be done gradually, under the supervision of your doctor.
  • Diabetes: The signs associated with low blood sugar may be more difficult to see while you are taking metoprolol. People with diabetes may have a harder time regulating their blood sugar levels when taking this medicine. If you have diabetes, discuss with your doctor how this medication may affect your condition, how your condition affects the administration and effectiveness of this medicine, and whether medical supervision is needed. specific. You will be kept under medical supervision while taking this medicine and your doctor may need to adjust your doses of diabetes medicine.
  • Dizziness or syncope: Metoprolol may cause side effects, including dizziness or fainting, soon after starting treatment. Do not drive a vehicle or do other potentially dangerous tasks until you know how this medicine works for you.
  • Hyperthyroidism (high level of thyroid hormones): Metoprolol may mask the symptoms of a person with hyperthyroidism (high level of thyroid hormones).
  • If you have hyperthyroidism, discuss with your doctor how this medication may affect your condition, how your condition affects the administration and effectiveness of this medicine, and whether it is appropriate to have it. specific medical surveillance. Stopping the medication suddenly could make this condition worse.
  • Liver function: Liver disease or reduced liver function can cause this drug to build up in the body, causing side effects. If you have liver problems, talk to your doctor about how this medicine may affect your condition, how your condition affects the administration and effectiveness of this medicine, and whether medical supervision is needed. specific. Your doctor will monitor your liver function with regular blood tests while you are taking this medicine.
  • If you notice symptoms of liver problems such as fatigue, feeling unwell, loss of appetite, nausea, yellowing of the skin or whites of the eyes, dark urine, pale stools, abdominal pain, or swelling and itching of the skin, contact your doctor immediately.
  • Kidney function: Taking metoprolol may affect kidney function. Your doctor will take this into account in his monitoring and will adjust your dose as needed. If you have reduced kidney function or kidney disease, talk to your doctor about how this medicine may affect your condition, how your condition affects the administration, and how well this medicine works. , and the relevance of specific medical surveillance. If you notice swelling in your hands, feet, or face, an increase in your blood pressure, unusual muscle cramps, or a dark appearance of your urine, this medicine may be interfering with the proper function of your blood. kidneys.
  • If you notice any of these symptoms, contact your doctor as soon as possible.
  • Heart disease: Beta-blockers like metoprolol can worsen already present heart failure. It is essential to use metoprolol as prescribed by your doctor to reduce this risk. If you have a history of heart disease, discuss with your doctor how this medication may affect your condition, how your condition affects the administration and effectiveness of this medicine, and whether it is appropriate to use it. specific medical surveillance.
  • Pheochromocytoma: This medicine may worsen the symptoms of pheochromocytoma (a tumor of the adrenal gland) if taken alone Talk to your doctor about how this medicine might affect your condition, how your condition affects your condition. administration and efficacy of this medicinal product, and the relevance of specific medical supervision.
  • Surgery: If you are about to have surgery, tell all healthcare professionals who treat you that you are using metoprolol.
  • Pregnancy: This medication should not be used during pregnancy unless the benefits outweigh the risks. If pregnancy occurs while you are using this medicine, contact your doctor immediately.
  • Breast-feeding: This medicine passes into breast milk. If you use metoprolol while you are breastfeeding your baby may feel the effects. Check with your doctor to see if you should continue breastfeeding.
  • Children: The safety and effectiveness of this medicine have not been established in children
  • Seniors: Normal doses of metoprolol for adults may lower blood pressure more than expected. Lower doses may be necessary for the elderly.
  • Can other agents interact with this medication?
  • There may be an interaction between metoprolol and any of the following:
  • abiraterone acetate;
  • acetylcholine;
  • anesthetic agents;
  • alpha agonists (eg, clonidine, methyldopa);
  • alcohol;
  • aldesleukin;
  • aliskiren;
  • alpha1-blockers (eg doxazosin, prazosin, tamsulosin);
  • amifostine;
  • amiodarone;
  • amphetamines (eg, dextroamphetamine, lisdexamfetamine);
  • serotonin antagonists (antiemetic drugs; eg dolasetron, granisetron, ondansetron);
  • tricyclic antidepressants (eg amitriptyline, clomipramine, desipramine, trimipramine);
  • antihistamines (eg, cetirizine, doxylamine, diphenhydramine, hydroxyzine, loratadine, diphenhydramine);
  • nonsteroidal anti-inflammatory drugs (NSAIDs) eg. ibuprofen, indomethacin, naproxen);
  • antimalarials (e.g. chloroquine, hydroxychloroquine, mefloquine, quinine);
  • antipsychotics (eg, chlorpromazine, clozapine, haloperidol, olanzapine, quetiapine, risperidone);
  • asunaprevir;
  • atomoxetine;
  • other beta-blockers (eg, atenolol, pindolol, propranolol);
  • azelastine;
  • barbiturates (eg, butalbital, pentobarbital, phenobarbital);
  • beta-agonists (anti-asthma medicines, eg salbutamol, salmeterol, formoterol);
  • calcium channel blockers (eg, verapamil, diltiazem, nifedipine, amlodipine);
  • angiotensin II receptor blockers (ARBs) eg. irbesartan, losartan);
  • bortezomib;
  • brimonidine;
  • buprenorphine;
  • bupropion;
  • celecoxib;
  • ceritinib;
  • milk thistle;
  • cholecalciferol;
  • cimetidine;
  • cinacalcet;
  • clobazam;
  • clotrimazole;
  • cobicistat;
  • cocaine;
  • cyproterone;
  • darifenacin;
  • delavirdine;
  • rye ergot derivatives (eg bromocriptine, ergotamine, methylergonovine);
  • nitro derivatives (eg nitroglycerin, isosorbide dinitrate, isosorbide mononitrate);
  • dextromethorphan;
  • digoxin;
  • dipyridamole;
  • disopyramide;
  • disulfiram;
  • diuretics (pills to remove water; eg furosemide, hydrochlorothiazide);
  • donepezil;
  • doxorubicin;
  • dronedarone;
  • entacapone;
  • epinephrine;
  • grass pollen allergen extract;
  • fentanyl;
  • fingolimod;
  • flecainide;
  • floctafenine;
  • galantamine;
  • ginger;
  • ginseng;
  • guanfacine;
  • imatinib;
  • phosphodiesterase type 5 inhibitors (eg, sildenafil, tadalafil);
  • proton pump inhibitors (eg, lansoprazole, omeprazole, rabeprazole);
  • Angiotensin-Converting Enzyme Inhibitors (ACEIs) eg. captopril, ramipril);
  • selective serotonin reuptake inhibitors (eg fluoxetine, paroxetine, sertraline);
  • selective serotonin-norepinephrine reuptake inhibitors or SNRIs (eg, desvenlafaxine, duloxetine, venlafaxine);
  • insulin;
  • isoniazid;
  • ketoconazole;
  • lacosamide;
  • lanreotide;
  • levodopa;
  • lidocaine;
  • lomustine;
  • cholesterol “statin” drugs (eg pravastatin, simvastatin);
  • methacholine;
  • methadone;
  • methimazole;
  • methoxsalen;
  • methylphenidate;
  • metoclopramide;
  • midodrine;
  • mifepristone;
  • mirabegron;
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  • moclobemide;
  • nefazodone;
  • nevirapine;
  • nilotinib;
  • noradrenaline;
  • octreotide;
  • orphenadrine;
  • oxybutynin;
  • pasireotide;
  • pazopanib;
  • peginterferon alfa-2b;
  • pentoxifylline;
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  • sodium phenylbutyrate;
  • pilocarpine;
  • pimozide;
  • praziquantel;
  • propafenone;
  • quinidine;
  • quinine;
  • ranitidine;
  • regorafenib;
  • rifabutin;
  • rifampin;
  • rituximab;
  • rivastigmine;
  • ropinirole;
  • sulfonylureas (eg gliclazide, glyburide, tolbutamide);
  • temsirolimus;
  • terbinafine;
  • theophyllines (eg aminophylline, oxtriphylline, theophylline);
  • ticagrelor;
  • ticlopidine;
  • tizanidine;
  • tofacitinib;
  • tolcapone;
  • tranylcypromine;
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  • yohimbine.
  • If you are taking any of the above medicines, please tell your doctor or pharmacist.  In your case, your doctor may ask you to:
  • stop taking any of the medications;
  • replace one of the drugs with another;
  • change the way you take one or both of the medicines.
  • do not change anything at all.
  • Interference of one medicine with another does not always mean that you stop taking one of them. Ask your doctor what to do with drug interactions.
  • Drugs other than those listed above may interact with this drug. Tell your doctor everything you take, whether it is prescription or over-the-counter drugs and herbal remedies. Do not forget to mention any supplements you take. If you consume caffeine, alcohol, nicotine, or street drugs, you should tell your prescribing doctor since these substances can affect the way many drugs work
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Side effects of too much cinnamon

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