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4 shocking health benefits of Rehmannia

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Discover the 4 shocking health benefits of Rehmannia.

In Traditional Chinese Medicine (TCM), Rehmannia is one of the top 50 foundational herbs used for the natural treatment of various health problems.

It is generally an option of choice for conditions believed to be the result of a yin deficiency.

In TCM, optimal health is believed to come from a proper balance of yin (negative, dark, and feminine) and yang (positive, bright, and masculine) energies in the body.


Both traditional Chinese medicine and Japanese medicine consider Rehmannia to be a “general tonic,” which means that it can help a wide variety of symptoms and health problems.

It is commonly combined with other herbs in traditional herbal medicine practices.

What is rehmannia specifically used to treat? Conditions include anemia, diabetes, fever, osteoporosis, and allergies.

What is Rehmannia?

There are hundreds of herbs that are commonly used in both traditional Chinese medicine and traditional Japanese medicine, such as Dong Quai,  ginseng, cinnamon bark, ginger,  astragalus,   and this lesser-known herb called rehmannia.


Rehmannia is a type of perennial flowering plant that occurs in six species: Rehmannia chingii, Rehmannia elata, Rehmannia glutinosa, Rehmannia henryi, Rehmannia Piasecki, and Rehmannia solanifolia, all belonging to the Orobanchaceae family. Rehmannia glutinosa is the most common variety used in TCM.

The leaves of the plant are mainly at ground level and its flowers can range from yellow to burgundy. Both the rehmannia root and the above-ground parts are used to create the medicine.

It is one of the best herbs used in natural health treatments


Other names for rehmannia include Chinese foxglove, Chinese Radix rehixniae, Chinese RR, Di Huang, Gun-Ji-Whang, Japanese Rehmanniae Radix, Shu Di Huang, Sook-Ji-Whang, and To-Byun.

The use of the herb’s name can vary depending on whether it is fresh, dried, or cooked.

Why is it possible that rehmannia can have positive health effects? The plant’s chemical constituents are believed to help lower blood sugar, reduce pain, decrease swelling, and positively impact the immune system.

According to the research, the least 12 chemical substances have been isolated from the root of the plant rehmannia, including the tyrosol acetonide, the leucosceptosido A, martinesido, the isomartinosido, the purpureasida C, the jionósido A1, and jionósido B1.


Meanwhile, there are at least six chemical constituents of aerial or aerial parts, such as aegenetic acid, corchorifattty acid B, and pinelic acid.

According to TCM, the properties of foxglove are sweet, bitter, and cold, and it can affect the meridians of the heart, liver, stomach, and kidneys.

Its main actions include nourishing the yin, removing heat from the blood, and stopping bleeding. It is also commonly used in traditional  Chinese medicine for adrenal problems.

By looking at this herb online, you can find Rehmannia 8, which is a supplement that is a special proprietary blend of Rehmannia and seven additional herbs. It is said to be based on a popular traditional formula called Jin Gui Shen Qi Wan.


4 Potential Health Benefits and Uses of Rehmannia

Medical experts sometimes question the benefits of Rehmannia, as research has been done primarily with animals, and/or Rehmannia is often used in combination with other herbs, but let’s take a look at what some of the more recent studies say about it. interesting herbal remedy.

1.- Anti-diabetes

A study published in 2018 looked at the potential blood sugar-lowering effects of catalpol, which is a natural product isolated from the root of Rehmannia glutinosa.

In vivo and in vitro research with type 2 diabetes-induced animal subjects found that the rehmannia product could improve hepatic insulin resistance in type 2 diabetes, specifically by acting on the AMPK / NOX4 / PI3K / AKT pathway.

Another animal study published in the peer-reviewed journal Biomedicine & Pharmacotherapy evaluated the impact of aqueous extracts of Yangkyuksanhwa-tang (YKSHT) and one of its main components, Rehmannia glutinosa (RG), on type 2 diabetes. In Korean medicine, Yangkyuksanhwa-tang is often prescribed for this form of diabetes.


The researchers found those subject mice treated with RG or YKSHT showed a decrease in blood glucose levels.

Furthermore, both extracts appear to reduce grehlin (also known as the ‘hunger hormone’) and have ‘weight control effects’.

2.- Neuroprotective

Catalpol, an iridoid glycoside isolated from Rehmannia glutinosa root, is known to have a positive effect on neurodegeneration, which plays an important role in chronic health problems such as dementia and  Alzheimer’s’s’s disease.

Neurodegenerative disorders like these are marked by a loss of neurons in the brain and/or spinal cord.


One study points to the neuroprotective activities of catalpol, including its useful effects on calcium concentration, protein expression, and signaling pathways in the brain, resulting in reduced neuron loss.

3.- Possible helper of osteoporosis

In traditional Chinese medicine, the anti-osteoporotic effects of rehmannia are said to be the result of the herb’s ability to regulate kidney and liver function while increasing blood circulation.

A scientific review includes traditional Chinese medicinal uses, phytochemistry, pharmacokinetics, and pharmacology of rehmannia about osteoporosis, a disease that causes a decrease in bone density and quality.


For this recent scientific review, more than 300 research articles and reviews were analyzed.


The review found 107 clinical trials that used rehmannia along with additional herbs to treat postmenopausal, senile, and secondary osteoporosis.

According to the review, “most clinical trials are characterized by high efficacy and have no obvious adverse effects.

However, the efficacy of these clinical trials is limited due to the small patient sample size, short duration of treatment, and poor clinical design. Also, the TCM herbs in the clinical study are unclear due to a lack of standardization and authentication.

Overall, the review concludes: ‘Well-designed and well-controlled prospective studies are still needed to further demonstrate the bone-protective actions and safe use of this herb and its ingredients.’


4.- Helps atopic dermatitis

In traditional Chinese medicine, rehmannia is sometimes used to treat allergy-related problems.

An animal study evaluated the herb’s effects on atopic dermatitis, an itchy skin inflammation. This skin condition can often be caused by an allergic reaction.

For this study, the researchers topically applied an extract of the herb to mite allergen-induced atopic dermatitis in mouse subjects.

What did the researchers find? The herbal extract was able to inhibit the development of atopic dermatitis in animals, by suppressing the expression of cytokines, chemokines, and adhesion molecules.


The herb has also been studied for use in canine atopic dermatitis along with white peony (Paeonia lactiflora ) and licorice ( Glycyrrhiza glabra ).

Researchers at the University of Minnesota studied 50 atopic dogs in a randomized, double-blind, placebo-controlled trial.

Dogs treated with the herbal mix saw a 37.5 percent improvement compared to a 13 percent improvement in the placebo group. However, this was not considered a statistically significant difference.

History and interesting facts

The plant is endemic to countries in Asia, including China, Japan, and Korea. It was brought from Asia to the western world in the 18th century. In the United States and Europe today, it is sometimes grown as an ornamental garden plant.


The species name “glutinous” comes from glutinous and is a reference to the sticky nature of the plant’s root. In China, its name means “big yellow” or “yellow earth.”

Rehmanniae Radix is the tuber from the root of Rehmannia glutinosa and is said to be one of the most common ingredients in multiple Chinese herbal medicine formulas recommended for aging-related memory impairment.

Rehmannia precautions

Rehmannia can lower blood sugar and therefore interact with antidiabetic medications.

Since taking it can affect blood sugar levels, people with diabetes are generally advised to avoid or use extreme caution when taking this herb, and people undergoing surgery should stop taking it at least two weeks before. or earlier, according to the doctor’s recommendations.


It is not recommended for children, pregnant women, or breastfeeding women. The herb is also not recommended for people with chronic liver disease or gastrointestinal disease.

When it comes to TCM, it is key to research and visits a professional who is well trained and certified.

All Chinese herbal remedies, such as rehmannia, should be taken under professional supervision.

There is currently no established recommended safe dosage for this herb, so speak with your healthcare provider about the appropriate dosage for your needs.


Many supplements made from this herb contain between 55 and 350 milligrams of the herb.

I also want to point out that Chinese herbal products made outside of the US can be mislabeled, contain dangerous additives, and sometimes have small amounts of dangerous heavy metals.

Look for high-quality, pure products made from trusted, certified retailers, or work directly with an herbalist.

According to TCM, this herb is generally contraindicated if you have diarrhea or bloating due to spleen deficiency.


Side effects of this herb that have been reported include gastrointestinal upset (mild nausea, loose intestines, flatulence), allergy, headache, dizziness, palpitations, fatigue, and vertigo.

Final thoughts on the Rehmannia

• It is a flowering plant that comes in six varieties. It is the most used for health purposes.

• Both the root and the parts above the ground are used to create the medicine.

• The herb is commonly used in traditional Chinese medicine, Japanese medicine, and Korean medicine.


• Research has been conducted primarily with animals or in combination with other herbs, but studies point towards potential benefits for diabetes, obesity, neurodegenerative diseases, bone diseases such as osteoporosis, and allergy-induced atopic dermatitis


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