Weight loss

Metformin weight loss: how to lose weight with metformin

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Discover metformin weight loss secret 2022.

Metformin is a drug intended to treat patients with Type 2 diabetes, but it comes with an exciting side effect: weight loss.

And Reddit is loaded with stories from people who have lost weight on the drug. “Was trying to lose weight for a long time with no success,” one person composed of being prescribed metformin.

“I’m on 1000 mg a day and am down 10 pounds.” “I saw weight loss at first with 500 mg twice per day,” another wrote. “The difference was nearly immediate.”

How to lose weight


While some people say the medicine didn’t do much for them, others swear by it—even those that don’t have Type 2 diabetes, says Fatima Cody Stanford, M.D., an instructor of medicine and pediatrics at Harvard Medical School and obesity medicine physician at Massachusetts General Hospital.


Cody Stanford says that she often designates the medication for overweight or obese people who don’t have Type 2 diabetes.

Metformin isn’t a weight-loss medication, but researchers have discovered a link connecting metformin and weight loss.

A long-term study published in the journal Diabetes Care that was conveyed by the Diabetes Prevention Program resolved that the drug could serve as a treatment for excess body weight, although more studies are needed.

Metformin weight loss Pictures

How metformin work

Metformin causes a reduction in the release of glucose from a person’s liver.

This serves to lower a person’s blood sugar when it’s too high and restore the way someone uses food to make energy, according to the Mayo Clinic. “Weight loss can occur because it decreases appetite in some people who take it,” says women’s health expert Jennifer Wider, M.D.


For the medicine to work effectively, the amount of metformin you take must be matched against your diet and exercise because it improves level out your blood sugar, the clinic says.

For that reason, if you improve your diet or exercise, your doctor may need to change the amount of metformin you take.

Can Non-Diabetics Take Metformin?

What if you don’t have type 2 diabetes? Can you still take metformin for weight loss? This is an outstanding question, and the quick answer is yes. Metformin has been used off-label, or outside its expected purpose, for weight control.

A review published in December 2018 in the European Journal of Clinical Pharmacology examining the efficacy of metformin for weight loss in overweight and obese people outwardly diabetes decided that the drug could significantly lower body mass index in both adolescents and adults.

But because this drug is only available by prescription and hasn’t been recommended for weight loss by the Federal Drug Administration, your doctor will likely first suggest some of these traditional strategies for weight loss:

  • Avoid sugary beverages.
  • Drink water before meals to fill your belly so that you eat less.
  • Exercise for 30 minutes most days of the week.
  • Prepare whole foods, such as fruits, vegetables, and grains.
  • Restrict your intake of processed foods.
  • Eat a high-protein, low-carb, low-fat diet.
  • Practice portion control.
  • If you don’t have type 2 diabetes, your doctor may sign off on this drug if you’re obese and trying to lose weight. But again, metformin isn’t a replacement for healthy eating and daily exercise, which are keys to sustainable weight loss. These habits also promote weight loss if you have type 2 diabetes but can’t take metformin.

“For those patients with diabetes who can’t take metformin, due to chronic kidney disease or other matters, diet and lifestyle adjustments will still be of absolute importance, whether they’re prescribed alternate medication or not. Controlling carbohydrate intake, increasing physical activity, and managing stress is the cornerstone of improving glycemic control,” says Magnotta.


“Make it a point to stand up every hour or so and walk around the room, the yard, or the block. Little bits of physical activity over the day add up, resulting in the burning of more calories as a result,” she says.

Does Metformin Cause Weight Loss

Cody Stanford says she uses the medicine often in her practice among those with and without Type 2 diabetes—and it works. “While metformin is typically prescribed for the treatment of Type 2 diabetes, it has been shown to produce weight loss in some individuals with a low likelihood of adverse effects,” she says.

Here’s why: Notwithstanding whether or not the patient taking metformin has Type 2 diabetes or insulin resistance, the medicine can enhance a person’s insulin sensitivity.

That increased sensitivity to insulin can keep a person’s blood sugar level, which prevents the hunger and carb desires that come with spikes and following drops in blood sugar, Stanford explains. And with less desire and carbs, you’re more likely to have a more relaxed time losing weight.

The meds also reduce a person’s glucose levels, which produces a lesser likelihood that excess sugar will be stored as fat tissue in the body, she says.

Finally, the drug can increase a person’s sensitivity to leptin, a hormone that makes you feel full and might improve your metabolism, Stanford says.


Metformin dosage for weight loss

The specific dosage of metformin that people should take will alter. A person should talk to their doctor about proper dosage and report any side effects after taking the medicine.

The dosage of metformin is based on someone having type 2 diabetes. How much a person takes depends on the kind of metformin and the brand. People can take some types of medication with meals, some on their own, and others with insulin.

Some of the dosage recommendations and guidelines include:

  • For lengthened-release metformin and tablets, doses are between 500 and 1000 milligrams (mg) and should not exceed 2,500 mg in a day for adults.
  • For liquid forms, doses range between 5 and 8.5 milliliters (ml) for adults, and should not exceed 25 ml a day.
  • Children taking liquid forms typically use 5 ml twice a day. For most forms, children should follow doses recommended by their doctor.

If somebody misses a dose of metformin, they should try to take it as soon as possible. If they are very close to their next scheduled dose, the missed dose should be skipped. It is not recommended to double up on doses of metformin.


As always, a person should speak to their doctor about proper dosage and any changes in their medication.

2 month metformin weight loss results

Amanda M says


I was diagnosed with PCOS about 2 weeks ago. When I first started taking it the nausea was bothersome but a couple days in, it was gone. I have been taking this for 6 weeks now and have lost 7 lbs!

Ally says

I was put on 500mg of metformin 3 times per day after being told I had Type II. After struggling to lose weight for many years, I lost 6 lb in the first week.

By the end of year one I have lost 2 stone. I noticed that the fat started to melted off my legs and arms within weeks. I look great and feel amazing. I did start eating healthier, but I then found that my appetite disappeared, I drank excessively, had more hot flushes than usual.

Never felt sick or had upset tummy. I would recommend Metformin to help lose weight but you must put a bit of effort in too.

You find that your appetite disappears anyway so you may aswell eat healthier. It turns out that Type II was the best thing to happen to me because I have now lost all of my excess weight and am now Type II free !!


PaIge says

I have lost 40 pounds on metformin

Pamela says

i have lost 40 pounds since starting metformin 7 months ago. I’m never hungry

Denis says

I have been taking Metformin for 6 months and have lost 36 lbs. Another half a year and I should be able to put on my old Army uniform.


Metformin weight loss diet plan

Currently research on this topic is still going on.

Metformin weight loss pcos

Weight loss is a characteristic of rambling metformin therapy in obese women with PCOS, with greater weight loss potentially possible with higher doses. More studies are expected to deduce whether other facets of the disorder may benefit from the higher dose of metformin.

Best time to take metformin for weight loss

500 mg metformin alone should be taken once daily with the evening meal. Your physician may increase your dose if desired until your blood sugar is regulated.

Nonetheless, the dose is usually not more than 2000 mg per day.

Metformin side effects weight loss

All things supposed, metformin can cause a weight loss, most likely due to side effects, like a decreased appetite and an upset stomach.

Even though effective for weight loss, the drug doesn’t replace conventional dieting methods.


So if you’re glimpsing to lose more and keep the weight off longer, you have to get active and eat carefully.

Is Metformin Dangerous?

The medicine is considered safe to use, but the Mayo Clinic notes that it can be negatively associated with certain medications like aspirin.

It’s also not suggested that you drink alcohol on metformin, and you should be careful about using the drug if you have conditions like anemia or a vitamin B12 deficiency. People with kidney and liver problems should also steer clear, Wider says.

The most frequent side effects of using metformin are nausea, loose stools, and abdominal pain, Stanford says. Obviously, it’s essential to take the drug under a doctor’s care.

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