Categories: Side effects

Contraindications and side effects of Sintrom

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Discover the Contraindications and side effects of Sintrom.

Sintrom is a well-known and popular blood-thinning drug. Helps control blood clotting so that clots do not form.

What it does is help the blood to stay liquid so that blood clots, such as thrombi, cannot form and prevent a stroke from occurring.

It is especially useful in people who have had a stroke, which is commonly known as a stroke.

However, it is as effective as it is dangerous and its use has to be strictly controlled. It should be monitored periodically and the doses should be administered as indicated.

Also, not all people can take it. In this article, we explain what the contraindications and side effects of Sintrom are.Contraindications and side effects of Sintrom


What is Sintrom for

Clotting is an important process in the body as it helps repair injuries. The problem is that some conditions cause the blood to clot without injury and this causes clots to form in the blood vessels, blocking them.

For these cases, it is administered Sintrom whose active ingredient is Acenocumarol, which acts as an antagonist of vitamin K.


This vitamin acts in the body as a blood coagulant and is an anti-hemorrhagic vitamin. Sintrom, for its part, acts as an anticoagulant and prevents the formation of thrombi and emboli.

EIt is used in people who are at high risk of thrombosis or conditions that cause blood clots, for example, to prevent a stroke.

Clots are made up of a protein called fibrin and platelets. Fibrin also contributes to blood clotting. Sintrom inhibits the formation of fibrin, helping to prevent blood clots from forming.

Next, we detail what are the main medical indications for the administration of Sintrom :

•Acute myocardial infarction

•Venous thromboembolism

•In people with prosthetic heart valves.

•Atrial fibrillation


•Stroke or stroke


•Valvular disease

•Dilated cardiomyopathy

Sintrom contraindications

Although it is a very effective drug, not everyone can take it as it affects blood clotting and can be dangerous. The main contraindications of Sintrom are the following:

•People with an allergy to acenocoumarol or any of the components or excipients of Sintrom.

•Children and the elderly will always take it strictly following the indications since they are more susceptible to this drug. Check-ups should be done from time to time and greater caution should be exercised in the doses administered.

•People with an allergy or intolerance to lactose as it is among its components. For this, it is better to go to the specialist and he will be the one who prescribes the appropriate dose.


•People with mental problems or who are senile or have some memory disease should have someone to help them with the taking as they could forget the dose or confuse them.

•When there is a risk of bleeding, the use of Sintrom should be avoided as it could worsen the situation. For example, some diseases such as hemophilia or gastrointestinal ulcers can cause bleeding.


•If you are pregnant or suspect that you are, as it could cause congenital malformations in the fetus.

•People with heart disease.

•People with high blood pressure, liver failure, or severe kidney failure.

•After an operation, since in these cases there is an increase in fibrinolytic activity.

In addition, you should consult your doctor if you are taking any other medication as they could act oppositely.

Possible side effects of Sintrom

Sintrom, like the rest of drugs, has possible side effects that you should be aware of.


Mainly the most dangerous and common side effect of Sintrom is bleeding which can be very serious depending on the situation. But, apart there are other side effects of Sintrom are the following:

•More or less intense hemorrhages are located in the gums or nose, although they can also cause more serious bleeding such as gastrointestinal or urogenital.

•You are also likely to pass blood when you cough or sneeze or even vomit. Stools may also be bloody or appear black, signifying the presence of blood in the intestine.

•The menstrual period may be more bleeding than normal or even last more days than usual.

•Fever or headaches

•Some foods modify the effectiveness of Sintrom so it is advisable to ask your doctor about the diet as it could have adverse effects due to the interaction of the food and the medicine, mainly causing allergies, vomiting, and/or diarrhea.

•If you notice any signs, go to a doctor immediately as it could be an effect of the medication.

How to take Sintrom

Before knowing how to take Sintrom, blood tests should be done to see the level of INR, a parameter that measures the level of blood clotting. Coagulation is determined by several factors such as the level of platelets, fluids, etc.


When the INR is high it means that the dose of Sintrom administered is higher than necessary and the blood is too fluid, which can cause bleeding.

This side effect can be very serious because if, for example, the person has a wound, it will not heal properly and the blood will not stop coming out as it is too liquid and proper clotting does not occur.

On the other hand, if the INR is low, the administered dose will be insufficient and an increase will be required.

If the normal INR means that he has correct clotting, but this does not mean that he is stable since if the person has clotting problems it is as if he were not taking the medication and that is why the dose must be increased.

Before taking it, in the consultation, it is very important to inform your doctor of taking other medications, even if it is a painkiller taken sporadically.

Any other medicine should be consulted with the doctor since Sintrom could react negatively and in this way interactions of Sintorm with other medicines will be avoided.

In addition, alcoholic beverages should not be drunk while taking Sintrom and smoking should be avoided.

Its intake is daily and orally and together with the medication the doctor will assign you a follow-up sheet and exact doses and doses so that there is the greatest possible control.


This way you will know with the greatest accuracy what dose you have to take each day and at what times. The doses will depend on the treatment of the person and are always personalized and strictly indicated.

In addition, you should periodically go for blood tests to continue assessing INR levels and change medication if necessary.

This article is merely informative, at HBO we do not have the power to prescribe any medical treatment or make any type of diagnosis. We invite you to see a doctor in the case of presenting any type of condition or discomfort.


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